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Wholesale gelatin for capsule
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Wholesale gelatin for capsules

Our wholesale gelatin as a special pharmaceutical accessories for soft capsule and hard capsule, which together with drugs into the human digestive system, and finally absorbed by the human body. Our wholesale gelatin have many properties such as gelatin ability, water retention, adhesion and solubility.

As well as its chemical purity, gelatin has a wide range of uses in the pharmaceutical industry. The most important of which are hard capsules, soft capsules,plasma and coating and so on.

Our wholesale gelatin for capsule is purified by incomplete acid hydrolysis, alkaline hydrolysis or enzymatic degradation of collagen from animal skin, bone,tendon and ligament, or a mixture of the above three different gelatin products.

Wholesale-gelatin-for-capsules-china​

Specification of our wholesale gelatin for capsules

Our wholesale gelatin is slightly yellow to yellow, transparent or translucent microstrip luster flakes or powder;Odorless, tasteless;leaching
It swells and softens in water, absorbing five to 10 times its own mass. It can soluble in hot water, soluble in acetic acid or glycerin and water hot mixture,
insoluble in ethanol.

How to identify our wholesale gelatin for capsules grade?

(1) take 0.5g of the product, add 50ml of water, heat to dissolve, take 5ml of the solution, accentuate potassium chromate test solution – dilute
Hydrochloric acid (4:1) mixture drops, that is, orange flocculent precipitation.
(2) Take 1ml of the remaining solution under identification (1), add 100ml of water, shake well, add a few drops of tannic acid test solution, that is, muddy
Turbidity.
(3) Take this product, add sodium lime, heating, that is, ammonia odor.

How to test our wholesale gelatin for capsules grade?

Jelly strength (gelatin for capsules use only)

Take two copies of this product 7.50g each, put them in a test bottle and add water to make the 6.67% glue solution was covered and placed for 1 to 4 hours. Then stirred and heated in a water bath at 65℃±2℃ for 15 minutes to dissolve the test product. Put the test product at room temperature for 15 minutes, horizontally put the test bottle in a constant temperature water bath of 10℃±0.1℃. Use the rubber to hold the stopper for 17 hours ±1 hour. Then quickly remove the test bottle, dry the outer wall, and place the test bottle to jelly strength test machine
on the test table to test and calculate. The average of the two results shows that the jelly strength should not have the difference between 10 bloom.

Viscosity

Take 4.5g of this product and put it in a weighed weight 100ml beaker, add 20ml warm water, put in a 60℃ water bath and dissolve by stirring. Take out the beaker, dry the outer wall, add water to make the total weight of the glue reach the weight of the following formula (including dry products 15.0%), after mixing the glue well, pour it into a dry conical bottle with a plug, close the plug, and place it in a water bath at 40℃±0.1℃. After the temperature reaches 40℃±0.1℃, move to pinghe viscometer, measure at 40℃±0.1℃ water bath according to the viscosity determination method .
Total weight of glue (g) =(1− Dry weight loss) 4.50╳100

PH

Take 1.0g of the product, add 100ml hot water, shake it thoroughly to dissolve it, cool it to 35℃, and measure it according to standard, pH value should be 4.0~7.2.

Transmittance

Take 2.0g of the product, add 50~60℃ water to dissolve and make a solution containing 6.67%, cool to 45℃, then illuminate purple external – visible spectrophotometry to determine transmittance at 450nm and 620nm, respectively should below 50% and 70%.

Electrical conductivity

Take 1.0g of the product and dissolve it in water not exceeding 60℃ to make a solution containing 1.0% as the test solution. Take another 100ml water as blank solution, and put the test solution and blank solution in a water bath of 30℃±1℃ for 1 hour.
After that, measure the electrode by conductivity meter, and use the platinum black electrode as the determination electrode. Rinseding the electrode with blank solution for 3 times, measure the conductivity of blank solution. The conductivity of the solution should not exceed 5.0μS/cm. Remove the electrode and rinse the electrode with the test solution for 3 times. After that, conductivity of the test solution should not exceed 0.5ms /cm.

Sulfites (SO 2)

Take 10.0g of this product and put it into a flask with long neck and round bottom, add 150ml water and leave it for 1 hour. Heating in a 60℃ water bath to dissolve, add 5ml phosphoric acid and 1g sodium bicarbonate to connect the condensing tube immediately (excessive foam is
generated, adding appropriate defoaming agent, such as silicone oil, etc.), add heating distillation, use 0.05mol/L iodine solution 15ml as the receiving solution, collect 50ml distillate, dilute it to 100ml with water, shake well, take 50ml, put it on water bath for evaporation.
Replenish the appropriate amount of water at any time, steam until the solution is almost colorless, dilute to 40ml with water, check by sulfate test. If turbidity appears, should no more dense (0.01%)compared to standard 7.5 mL potassium sulfate solution.

Peroxide

Take 10g of the product, put it into a 250ml stoppered flask, add 140ml water, place it for 2 hours. Heat it in a water bath at 50℃ for rapid dissolution, and cool it
immediately. Add 6ml of sulfuric acid solution (1→5) and 0.2g of potassium iodide.1% starch solution 2ml and 0.5% ammonium molybdate solution 1ml, packed,
shake well, put in the dark for 10 minutes, the solution should not show blue.

Loss on drying

Take this product, dry at 105℃ for 15 hours, weight loss should not exceed 15.0%.

Residue on ignition

Take 1.0g of this product, check according to standard, residual residue shall not exceed 2.0%.

Chromium

Take 0.5g of the product, place it in a polytetrafluoroethylene digestion tank, add 5~10ml nitric acid, mix well, and predigest 2 h at 100℃. After that, close the inner cover, tighten the coat, and place it in an appropriate microwave digestion furnace for digestion. After complete digestion, remove the inner tank. Heat it slowly on an electric heating plate until the red-brown vapor is exhausted and nearly dry. Transfer it into a 50ml TEflon measuring bottle with 2% nitric acid.

Dilute to scale, shake well, as the test solution;Prepare blank solution by the same method. In addition, take a standard chromium monoelement solution and use 2%nitric acid to dilute the standard chromium storage solution containing 1.0μg in 1ml. 

Proper amount of the solution was precisely taken and use 2% nitric acid solution to prepare 0~80ng chromium per 1mL as reference solution.Take the test solution and the reference solution, graphite furnace as the original neutralizer, atomic absorption spectrophotometry, determination at 357.9nm, or light inductance coupled plasma mass spectrometry.

The calculation is that it contains no more than two parts per million of chromium.If the test results need to be arbitrated, the inductively coupled plasma mass spectrometry (general rule 0412 first method) shall prevail.

Heavy metal

Take the residue left under Residue on ignition test, check according to standard, containing heavy metals shall not exceed ten parts per million.

Arsenic salt

Take 2.0g of the product, add starch 0.5g and calcium hydroxide 1.0g, add a small amount of water, stir evenly, after drying, use small flame burning to make carbonization first,
and then burn at 500~600℃ to make ash completely, cool, add 8ml hydrochloric acid and 20ml water to dissolve.
Check according to law (general rule 0822 First law), should comply with the provisions (0.0001%).

Microbial

Take this product and check according to standard, the total amount of aerobic bacteria in each 1g of the test product
should no more than 1000cfu, mold and yeast should no more than 100cfu of , no escherichia coli detected;Salmonella should not be detected in
each 10g sample

Our wholesale gelatin can made from what kinds of raw materials?

Our wholesale gelatin for capsules can mainly made from cow skin, cow bone, pig skin, pig bone, fish skin. Our wholesale gelatin for hard capsules usually requires the jelly strength at range 180-250bloom. Skin gelatin or bone gelatin can be used to produce hard capsules.
The price of bone gelatin will be relatively high. the higher jelly strength, the more expensive price is had. Wholesale gelatin for soft capsules usually requires the jelly strength at range 150-180 bloom. As a professional fish gelatin supplier and manufacturer, we suggest user to use fish gelatin for high appearance, if customers require the high quality wholesale gelatin.
Price for fish gelatin is higher because the production cost of fish gelatin is high.

 

What is the the function and efficacy of our wholesale gelatin for capsules?

Our wholesale gelatin capsules can help us relieve pain when we take them, because we all know that the drugs are mostly bitter, and we use capsules produced
by our wholesale gelatin can reduce the bitter taste and easy to stock. That is why the gelatin capsules medicine are popular in pharmaceutical gelatin line.
On the other hand, gelatin itself is extracted from animal skin or bone, it is a natural protein.
Gelatin capsules made from our wholesale gelatin do not cause any harm to our health, and we take good medicine without bitter taste.

Edible pork gelatin

We eat pork gelatin for a better body. And it can help our to keep healthy.

Gelatin for jelly

Best gelatin for jelly (carrageenan). Relative to the aforementioned protein reactivity and gelation.

Fish skin gelatin wholesale

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Adhesives use animal glue

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